Invitae Fatty Acid Oxidation Defects Panel
Analyzes genes involved in mitochondrial fatty acid oxidation to evaluate suspected FAODs. Supports diagnosis when symptoms, labs, or NBS findings suggest a defect.
Accessed through the Long-Chain Fatty Acid Oxidation Disorders Sponsored Testing Program•Sponsored by Ultragenyx Pharmaceutical, Inc.•Performed by Invitae | Labcorp
Designed to help patients understand the purpose of testing and what to expect.
For patients
What this test and program do
Long-chain fatty acid oxidation disorders (LC-FAOD) are rare conditions that affect how your body breaks down certain fats for energy, which can impact your muscles, heart, and liver. If your doctor suspects LC-FAOD, a sponsored program can help get answers through a comprehensive genetic test that looks at 25 genes related to fatty acid oxidation. The program is fully covered by Ultragenyx Pharmaceutical, so there is no cost to you, your doctor, or your insurance. Getting a clear genetic diagnosis can help your care team tailor a treatment plan and guide the best next steps for your health.
Who this may help
Could this be right for you or your family?
- To qualify, all of the following must be met:
- The patient lives in a country where the program is offered
- At least one of these is true:
- The patient has completed the UltraCare Start Form for LC-FAOD
- A doctor suspects or has diagnosed the patient with a long-chain fatty acid oxidation disorder, and a plasma acylcarnitine blood test has been ordered (abnormal or normal)
What to expect
How the process works
- 1
Discuss & Order
Talk with your provider about testing and give consent. Your provider will place the order through Invitae’s online portal.
- 2
Provide a Sample
Your provider will collect your specimen using an Invitae kit and return it to the lab. Most samples can be shipped at no additional charge from the US and Canada.
- 3
Get Results
Results are delivered online. Your provider will review them with you, and Invitae’s genetics experts are available if additional support is needed.
Cost & coverage
Understanding potential costs
If you qualify for this program, the sponsor works with the laboratory to help make testing more affordable. Many patients pay little or no out-of-pocket cost. Your exact cost will depend on your insurance coverage and the specific criteria of the program, and the lab can explain what to expect before your sample is processed.
Quality & privacy
How your sample and information are handled
Testing is performed by Invitae | Labcorp, a CLIA-certified laboratory (CLIA 05D2040778). Your sample is processed using validated methods and quality controls to support reliable genetic results.
Your health information is handled under privacy and security practices that are intended to align with applicable regulations. For program- and lab-specific details, review the privacy information provided by the laboratory and sponsor.
FAQ
Common questions about this program
What is the sponsored genetic testing program for long-chain fatty acid oxidation disorders?
The Long-Chain Fatty Acid Oxidation Disorders Program provides no-cost genetic testing for people who may have LC-FAOD. It uses the Invitae Fatty Acid Oxidation Defects Panel, which examines 25 genes involved in how the body transports and breaks down long-chain fats. The program is sponsored by Ultragenyx Pharmaceutical, and testing is performed by Invitae at Labcorp.
Is the LC-FAOD genetic test really free, and who pays for it?
Yes, the LC-FAOD genetic test through this program is completely free to you. Ultragenyx Pharmaceutical covers the full cost of testing, so there is no charge to you, your doctor, or your insurance plan. You will not receive a bill, a copay, or any hidden fees.
What kind of sample is needed for the LC-FAOD genetic test?
The Invitae Fatty Acid Oxidation Defects Panel can be performed using several sample types, including a blood draw, a saliva sample, a buccal swab (a gentle cheek swab), or extracted DNA. Your doctor's office will help you figure out which option works best for you or your child.
How long does it take to get results from the LC-FAOD genetic test?
Results from the Invitae Fatty Acid Oxidation Defects Panel are typically available within 10 to 21 days after the lab receives your sample. Your healthcare provider will review the results with you and discuss what they mean for your care. If you have questions while waiting, your doctor's office can help.
Is genetic counseling available through the LC-FAOD testing program?
Genetic counseling can be a helpful part of the testing process, and Invitae offers access to genetic counseling resources. A genetic counselor can help explain what your results mean, answer questions about LC-FAOD, and support you in making informed decisions about your health or your child's health.
Do I have to use a specific medication if I get tested through the LC-FAOD program?
No. Using this testing program does not require you or your doctor to prescribe, purchase, or use any product made by Ultragenyx Pharmaceutical. The program is offered to help you get a diagnosis and guide your care, with no strings attached.
Who qualifies for Long-Chain Fatty Acid Oxidation Disorders Long-Chain Fatty Acid Oxidation Disorders genetic testing?
Patients may qualify for Long-Chain Fatty Acid Oxidation Disorders if they meet the program's eligibility criteria:
- Resides in the United States or Canada.
- Meets one or more of the following:
- Has a completed UltraCare Start Form for LC-FAOD (include abnormal biochemical labs if available).
- Is suspected of, or has a confirmed diagnosis of, a long-chain fatty acid oxidation disorder and has had a plasma acylcarnitine test performed or ordered, regardless of result.
- Providing plasma acylcarnitine results or other confirmatory labs is encouraged to support accurate interpretation.
Questions to ask your doctor about Invitae Fatty Acid Oxidation Defects Panel
- Do you think this test is appropriate for me based on my symptoms and history?
- How could the results of this test change my diagnosis or treatment plan?
- What are the potential limitations of this test that I should understand?
- Should any of my family members also be tested based on my results?
- How will we follow up after the results are available?
Notes
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